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Cellular mechanisms of regulation of the inflammatory response in atherosclerosis: The role of cell contact-mediated signaling

Abstract:

The regulatory mechanisms of the inflammatory process in the atherosclerotic plaque are still not clearly understood. Stimulated T cells may have a key role in enhancing and perpetauting inflammation at the atherosclerotic site. They activate endothetial cells, macrophages and smooth muscle cells in the atherosclerotic plaque, not only via the production of soluble midiators, but also through cell-cell contact-mediated interactions (via membrane receptors and their ligands). Cell/cell contact...

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Italian Heart Journal Supplement
Volume:
2
Issue:
4
Pages:
339-343
Publication date:
2001-01-01
ISSN:
1129-4728
URN:
uuid:acdd7f4c-0b46-45d1-beb1-d9a8bef5033a
Source identifiers:
225663
Local pid:
pubs:225663

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