Journal article icon

Journal article

Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast.

Abstract:

Homologous recombination is believed to play important roles in processing stalled/blocked replication forks in eukaryotes. In accordance with this, recombination is induced by replication fork barriers (RFBs) within the rDNA locus. However, the rDNA locus is a specialised region of the genome, and therefore the action of recombinases at its RFBs may be atypical. We show here for the first time that direct repeat recombination, dependent on Rad22 and Rhp51, is induced by replication fork bloc...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/sj.emboj.7600670

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Journal:
The EMBO journal
Volume:
24
Issue:
11
Pages:
2011-2023
Publication date:
2005-06-05
DOI:
EISSN:
1460-2075
ISSN:
0261-4189
URN:
uuid:acd7ec89-b817-4c85-ba90-83929d7c4f61
Source identifiers:
99873
Local pid:
pubs:99873

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP