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A model of yeast cell-cycle regulation based on multisite phosphorylation.

Abstract:

In order for the cell's genome to be passed intact from one generation to the next, the events of the cell cycle (DNA replication, mitosis, cell division) must be executed in the correct order, despite the considerable molecular noise inherent in any protein-based regulatory system residing in the small confines of a eukaryotic cell. To assess the effects of molecular fluctuations on cell-cycle progression in budding yeast cells, we have constructed a new model of the regulation of Cln- and C...

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Publication status:
Published

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Publisher copy:
10.1038/msb.2010.55

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Journal:
Molecular systems biology
Volume:
6
Pages:
405
Publication date:
2010-08-01
DOI:
EISSN:
1744-4292
ISSN:
1744-4292
Source identifiers:
101157
Language:
English
Keywords:
Pubs id:
pubs:101157
UUID:
uuid:acd62cdc-b389-47cf-a787-6d0c79bfb063
Local pid:
pubs:101157
Deposit date:
2012-12-19

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