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Algorithms and software tools for ordering clone libraries: application to the mapping of the genome of Schizosaccharomyces pombe.

Abstract:

A complete set of software tools to aid the physical mapping of a genome has been developed and successfully applied to the genomic mapping of the fission yeast Schizosaccharomyces pombe. Two approaches were used for ordering single-copy hybridisation probes: one was based on the simulated annealing algorithm to order all probes, and another on inferring the minimum-spanning subset of the probes using a heuristic filtering procedure. Both algorithms produced almost identical maps, with minor ...

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Publication status:
Published

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Publisher copy:
10.1093/nar/21.8.1965

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Grigoriev, A More by this author
Hoheisel, J More by this author
Lehrach, H More by this author
Journal:
Nucleic acids research
Volume:
21
Issue:
8
Pages:
1965-1974
Publication date:
1993-04-05
DOI:
EISSN:
1362-4962
ISSN:
0305-1048
URN:
uuid:aca8a209-bc3b-4e50-a913-0c6e91c2217c
Source identifiers:
73833
Local pid:
pubs:73833

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