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Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.

Abstract:

BACKGROUND: Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation approach to test whether 25(OH)D concentration is causally associated with blood pressure and hypertension risk. METHODS: In this mendelian randomisation study, we generated an allele score (25[OH]D synthesis score) based on variants of genes that affect 25(OH)D synthesis o...

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Publication status:
Published

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Publisher:
Lancet
Journal:
lancet. Diabetes and endocrinology More from this journal
Volume:
2
Issue:
9
Pages:
719-729
Publication date:
2014-09-01
DOI:
EISSN:
2213-8595
ISSN:
2213-8587
Language:
English
Keywords:
Pubs id:
pubs:473988
UUID:
uuid:ac9c0c2d-1b80-4077-8a7f-03b8df926f0c
Local pid:
pubs:473988
Source identifiers:
473988
Deposit date:
2014-08-11

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