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Prognostic significance of hypoxia inducible factor-1α and vascular endothelial growth factor expression in patients with diffuse large B-cell lymphoma treated with rituximab.

Abstract:

We evaluated hypoxia inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) expression and their prognostic significance in diffuse large B-cell lymphoma (DLBCL). Expression of HIF-1α and VEGF was studied in 78 patients and results correlated with clinicopathological and prognostic data. HIF-1α and VEGF were expressed in 67% and 84% of patients, respectively, and a significant correlation was demonstrated between them (p < 0.001). Outcome was analyzed according to treat...

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Publication status:
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Authors


Powell, JR More by this author
Dojcinov, S More by this author
Wosniak, S More by this author
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Journal:
Leukemia and lymphoma
Volume:
54
Issue:
5
Pages:
959-966
Publication date:
2013-05-05
DOI:
EISSN:
1029-2403
ISSN:
1042-8194
URN:
uuid:ac767dce-5ae5-4333-b540-97b2d7a25ab9
Source identifiers:
356255
Local pid:
pubs:356255

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