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Journal article

Intramuscular loading dose of quinine for falciparum malaria: pharmacokinetics and toxicity.

Abstract:

In a study of intramuscular injection of quinine eight adults with moderately severe falciparum malaria resistant to chloroquine were treated with quinine dihydrochloride, being given a loading dose of 20 mg salt (16.7 mg base)/kg followed by three or four eight hourly maintenance doses of 10 mg salt (8.3 mg base)/kg injected into the anterior thigh. All patients responded to treatment. Fever and parasite clearance times (mean (SD) 60 (23) h and 53 (22) h respectively) were comparable with th...

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Publication status:
Published

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Journal:
British medical journal (Clinical research ed.)
Volume:
293
Issue:
6538
Pages:
11-13
Publication date:
1986-07-05
ISSN:
0267-0623
URN:
uuid:ac5d4d26-f653-4c6f-81a3-c1462406fb2a
Source identifiers:
61097
Local pid:
pubs:61097

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