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Journal article

Modelling of calcium handling in airway myocytes.

Abstract:

Airway myocytes are the primary effectors of airway reactivity which modulates airway resistance and hence ventilation. Stimulation of airway myocytes results in an increase in the cytosolic Ca(2+) concentration ([Ca(2+)](i)) and the subsequent activation of the contractile apparatus. Many contractile agonists, including acetylcholine, induce [Ca(2+)](i) increase via Ca(2+) release from the sarcoplasmic reticulum through InsP(3) receptors. Several models have been developed to explain the cha...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Progress in biophysics and molecular biology
Volume:
90
Issue:
1-3
Pages:
64-87
Publication date:
2006-01-01
DOI:
EISSN:
1873-1732
ISSN:
0079-6107
Source identifiers:
238419
Language:
English
Keywords:
Pubs id:
pubs:238419
UUID:
uuid:ac44a6a4-5580-497b-b307-687f6139068b
Local pid:
pubs:238419
Deposit date:
2013-11-16

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