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Histo-anatomical structure of the living isolated rat heart in two contraction states assessed by diffusion tensor MRI

Abstract:

Deformation and wall-thickening of ventricular myocardium are essential for cardiac pump function. However, insight into the histo-anatomical basis for cardiac tissue re-arrangement during contraction is limited. In this report, we describe dynamic changes in regionally prevailing cardiomyocyte (fibre) and myolaminar (sheet) orientations, using Diffusion Tensor Imaging (DTI) of ventricles in the same living heart in two different mechanical states. Hearts, isolated from Sprague-Dawley rats, w...

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Journal:
Progress in Biophysics and Molecular Biology More from this journal
Volume:
110
Issue:
2-3
Pages:
319-330
Publication date:
2012-10-01
DOI:
ISSN:
0079-6107
Language:
English
Keywords:
Pubs id:
pubs:359780
UUID:
uuid:ac419f35-eb64-4665-ac9f-7997a9962410
Local pid:
pubs:359780
Source identifiers:
359780
Deposit date:
2013-11-17

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