Biophysical properties of the eukaryotic ribosomal stalk.

Journal article

The landing platform for the translational GTPases is located on the 60S ribosomal subunit and is referred to as a GTPase-associated center. The most distinctive feature of this center is an oligomeric complex, the stalk, responsible for the recruitment of translation factors and stimulation of translation factor-dependent GTP hydrolysis. In eukaryotes, the stalk has been investigated in vitro and in vivo, but most information available concerns its individual components only. In the present ...

Expand abstract

Authors: Grela, P; Krokowski, D; Gordiyenko, Y; Krowarsch, D; Robinson, C

• Publication status: Published
• Journal: Biochemistry
• Volume: 49
• Issue: 5
• Pages: 924-933
• Publication date: 2010-02-01
• DOI: 10.1021/bi901811s
• EISSN: 1520-4995
• ISSN: 0006-2960
• Language: English
• Keywords: Biophysical Processes; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; GTP Phosphohydrolases; Ribosomes; Ribosomal Proteins; Eukaryota; Cell Proliferation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Genetic Engineering; Spectrometry, Fluorescence