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Androgen receptor CAG repeat length correlates with semen PSA levels in adolescence.

Abstract:

BACKGROUND: Androgens exert their action through the androgen receptor (AR). The length of the AR CAG repeat is inversely correlated to receptor function and short CAG length might be a risk factor for development of prostate cancer. Our aim was to investigate whether CAG repeat number might have an impact on prostate function in adolescence. METHODS: AR genotyping was performed by direct sequencing of leukocyte DNA from 274 military conscripts. All men underwent endocrine evaluation and sem...

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Publisher copy:
10.1002/pros.10366

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
The Prostate
Volume:
59
Issue:
3
Pages:
227-233
Publication date:
2004-05-05
DOI:
EISSN:
1097-0045
ISSN:
0270-4137
URN:
uuid:ac26d481-8f86-402f-9f4f-53a7edecd1ff
Source identifiers:
365993
Local pid:
pubs:365993

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