Journal article
Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies.
- Abstract:
-
Lysis of human lymphocytes by autologous complement had been studied using a range of monoclonal antibodies against different antigens. Antigen specificity (and not antibody isotype) was the most important factor which influenced cell lysis and this could not be accounted for merely by differences in surface density between antigens. Three antigens with comparable surface density were studied in detail: CAMPATH-1 (lytic), major histocompatibility complex class I (lytic) and leukocyte common a...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/eji.1830181006
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Authors
Bibliographic Details
- Journal:
- European journal of immunology
- Volume:
- 18
- Issue:
- 10
- Pages:
- 1507-1514
- Publication date:
- 1988-10-01
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- Source identifiers:
-
20327
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:20327
- UUID:
-
uuid:ac244151-d478-4336-89ed-678bab1eda87
- Local pid:
- pubs:20327
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1988
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