- Abstract:
-
The ataxic mouse mutant robotic is characterised by progressive adult-onset Purkinje cell loss that occurs in a distinctive region-specific pattern. We report the first behavioural characterisation of this mutant and quantify its performance on tests of motor function, locomotor and exploratory activity over a time course that reflects specific stages of cell loss in the cerebellum. Robotic mutants are significantly impaired on the rotarod and static rod tests of coordination and their perfor...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.bbr.2007.04.012
-
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- Journal:
- Behavioural brain research
- Volume:
- 181
- Issue:
- 2
- Pages:
- 239-247
- Publication date:
- 2007-08-05
- DOI:
- EISSN:
-
1872-7549
- ISSN:
-
0166-4328
- URN:
-
uuid:ac16a844-85f9-47bb-9228-6d6ffdd5f537
- Source identifiers:
-
106525
- Local pid:
- pubs:106525
- Copyright date:
- 2007
Journal article
Behavioural characterisation of the robotic mouse mutant.
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