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Journal article

Myocardial substrate metabolism in obesity.

Abstract:

Obesity is linked to a wide variety of cardiac changes, from subclinical diastolic dysfunction to end-stage systolic heart failure. Obesity causes changes in cardiac metabolism, which make ATP production and utilization less efficient, producing functional consequences that are linked to the increased rate of heart failure in this population. As a result of the increases in circulating fatty acids and insulin resistance that accompanies excess fat storage, several of the proteins and genes th...

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Publication status:
Published

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Publisher copy:
10.1038/ijo.2012.170

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
International journal of obesity (2005) More from this journal
Volume:
37
Issue:
7
Pages:
972-979
Publication date:
2013-07-01
DOI:
EISSN:
1476-5497
ISSN:
0307-0565
Language:
English
Keywords:
Pubs id:
pubs:356217
UUID:
uuid:abf99d3e-bada-46fc-b5ec-59f29ab40f99
Local pid:
pubs:356217
Source identifiers:
356217
Deposit date:
2013-11-16

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