Journal article icon

Journal article

Myocardial substrate metabolism in obesity.

Abstract:

Obesity is linked to a wide variety of cardiac changes, from subclinical diastolic dysfunction to end-stage systolic heart failure. Obesity causes changes in cardiac metabolism, which make ATP production and utilization less efficient, producing functional consequences that are linked to the increased rate of heart failure in this population. As a result of the increases in circulating fatty acids and insulin resistance that accompanies excess fat storage, several of the proteins and genes th...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/ijo.2012.170

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics, BHF Centre of Research Excellence
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
Journal:
International journal of obesity (2005)
Volume:
37
Issue:
7
Pages:
972-979
Publication date:
2013-07-05
DOI:
EISSN:
1476-5497
ISSN:
0307-0565
URN:
uuid:abf99d3e-bada-46fc-b5ec-59f29ab40f99
Source identifiers:
356217
Local pid:
pubs:356217

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP