Thesis
Arginine transport and other determinants of nitric oxide production in human septic shock
- Abstract:
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The arterial vasodilation seen in human septic shock is conventionally attributed to increased nitric oxide (NO) production, primarily by extrapolation of animal and cellular studies. Little is known of the cellular source of NO in human septic shock. Other mediators, such as carbon monoxide (CO), may modulate NO production, and could also directly contribute to vasodilation.
This study has examined the NO and CO synthetic pathways in peripheral blood mononuclear cells and mesenter...
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Bibliographic Details
- Publication date:
- 2002
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Source identifiers:
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603824078
Item Description
- Language:
- English
- Subjects:
- UUID:
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uuid:abf881fc-3c9a-40b4-89e1-07b8df2067d1
- Local pid:
- td:603824078
- Deposit date:
- 2014-04-01
Terms of use
- Copyright holder:
- Michael C. Reade
- Copyright date:
- 2002
- Notes:
- This thesis was digitised thanks to the generosity of Dr Leonard Polonsky.
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