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A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort.

Abstract:

Human Immunodeficiency Virus (HIV) and Hepatitis C virus (HCV) co-infection is recognized as a major cause of morbidity and mortality among HIV-1 infected patients. Our understanding of the impact of HIV infection on HCV specific immune responses and liver disease outcome is limited by the heterogeneous study populations with genetically diverse infecting viruses, varying duration of infection and anti-viral treatment.Viral-specific immune responses in a cohort of 151 HCV mono- and HIV co-inf...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0158037

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Weatherall Insti. of Molecular Medicine
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Weatherall Insti. of Molecular Medicine
Role:
Author
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Grant:
2012ZX10001006-001-008 and 2013ZX10001004-001-002
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS One Journal website
Volume:
11
Issue:
7
Pages:
e0158037
Publication date:
2016-07-25
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
pubs:abdbabc2-43d8-409a-8415-cce33c01913b
Source identifiers:
636344
Local pid:
info:fedora/pubs:636344
Language:
English

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