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Journal article

Pharmacological targets in the ubiquitin system offer new ways of treating cancer, neurodegenerative disorders and infectious diseases.

Abstract:

Recent advances in the development and discovery of pharmacological interventions within the ubiquitin-proteasome system (UPS) have uncovered an enormous potential for possible novel treatments of neurodegenerative disease, cancer, immunological disorder and microbial infection. Interference with proteasome activity, although initially considered unlikely to be exploitable clinically, has already proved to be very effective against haematological malignancies, and more specific derivatives th...

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Publication status:
Published

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Publisher copy:
10.1017/s1462399411002031
Journal:
Expert reviews in molecular medicine More from this journal
Volume:
13
Pages:
e35
Publication date:
2011-01-01
DOI:
EISSN:
1462-3994
ISSN:
1462-3994
Language:
English
Keywords:
Pubs id:
pubs:220556
UUID:
uuid:abcfa29b-c6bd-4ae2-815e-51a0610deaea
Local pid:
pubs:220556
Source identifiers:
220556
Deposit date:
2012-12-19

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