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Class-II and IL2 receptor positive cells in the pancreas of NOD mice.

Abstract:

The aberrant expression of Class-II molecules on pancreatic B cells in Type 1 (insulin-dependent) diabetes is still a matter of debate. In order to verify if Class-II molecules are expressed on islet cells in the NOD mouse we have studied 21 female mice of different ages (5 to 22 weeks). Serial cryostat pancreas sections were stained with monoclonal rat antibodies against Class-II antigens (P7/7) and the IL2 receptor (AMT-13). Our results show no Class-II expression by endocrine cells at any ...

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Publisher copy:
10.1007/BF00274802

Authors


Publisher:
Springer-Verlag
Journal:
Diabetologia More from this journal
Volume:
30
Issue:
11
Pages:
902-905
Publication date:
1987-11-01
DOI:
EISSN:
1432-0428
ISSN:
0012-186X
Language:
English
Keywords:
Pubs id:
pubs:35302
UUID:
uuid:abbc091a-f532-4632-976d-f20d5843c912
Local pid:
pubs:35302
Source identifiers:
35302
Deposit date:
2012-12-20

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