Journal article
Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in mice.
- Abstract:
-
To establish whether the combination of anti-resorptive therapy with mechanical loading has a negative, additive or synergistic effect on bone structure, we assessed the separate and combined effects of risedronate and non-invasive dynamic loading on trabecular and cortical bone. Seventeen-week-old female C57BL/6 mice were given daily subcutaneous injections of vehicle (n=20) or risedronate at a dose of 0.15, 1.5, 15 or 150 μg/kg/day (n=10 in each) for 17 days. From the fourth day of treatmen...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Bone
- Volume:
- 49
- Issue:
- 1
- Pages:
- 133-139
- Publication date:
- 2011-07-01
- DOI:
- EISSN:
-
1873-2763
- ISSN:
-
8756-3282
- Source identifiers:
-
149737
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:149737
- UUID:
-
uuid:abaf98a3-e9d9-4355-a36e-2f8cfb7ec368
- Local pid:
- pubs:149737
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2011
If you are the owner of this record, you can report an update to it here: Report update to this record