Journal article icon

Journal article

Maternally transferred antibodies from DNA-immunized avians protect offspring against hepadnavirus infection.

Abstract:

The outcome and protective efficacy of maternal antibodies elicited by DNA immunization to the large (L) hepadnavirus envelope protein were studied using the duck hepatitis B virus (DHBV) model. Following genetic immunization of breeding ducks with a DHBV L protein gene-bearing plasmid, specific and highly neutralizing antibodies were transferred from the sera of immunized ducks, via the egg yolk, to the progeny of vaccinees. Interestingly, large amounts (60 to 100 mg/egg) of high-titer and L...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
Journal of virology
Volume:
74
Issue:
10
Pages:
4908-4911
Publication date:
2000-05-01
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
Source identifiers:
111155
Language:
English
Keywords:
Pubs id:
pubs:111155
UUID:
uuid:abaa7cf1-809a-46e6-98af-220a46e3d5ee
Local pid:
pubs:111155
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP