Journal article
Maternally transferred antibodies from DNA-immunized avians protect offspring against hepadnavirus infection.
- Abstract:
-
The outcome and protective efficacy of maternal antibodies elicited by DNA immunization to the large (L) hepadnavirus envelope protein were studied using the duck hepatitis B virus (DHBV) model. Following genetic immunization of breeding ducks with a DHBV L protein gene-bearing plasmid, specific and highly neutralizing antibodies were transferred from the sera of immunized ducks, via the egg yolk, to the progeny of vaccinees. Interestingly, large amounts (60 to 100 mg/egg) of high-titer and L...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of virology
- Volume:
- 74
- Issue:
- 10
- Pages:
- 4908-4911
- Publication date:
- 2000-05-01
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- Source identifiers:
-
111155
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:111155
- UUID:
-
uuid:abaa7cf1-809a-46e6-98af-220a46e3d5ee
- Local pid:
- pubs:111155
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2000
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