Journal article icon

Journal article

Haptoglobin and sickle cell polymorphisms and risk of active trachoma in Gambian children

Abstract:

BACKGROUND: Susceptibility and resistance to trachoma, the leading infectious cause of blindness, have been associated with a range of host genetic factors. In vitro studies of the causative organism, Chlamydia trachomatis, demonstrate that iron availability regulates its growth, suggesting that host genes involved in regulating iron status and/or availability may modulate the risk of trachoma. The objective was to investigate whether haptoglobin (Hp) haplotypes constructed from the functiona...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0011075

Authors


Publisher:
Public Library of Science
Journal:
PLoS One More from this journal
Volume:
5
Issue:
6
Article number:
e11075
Publication date:
2010-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
pubs:60674
UUID:
uuid:ab9db1d4-5ca3-49b0-8020-2dccb771a764
Local pid:
pubs:60674
Source identifiers:
60674
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP