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Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.

Abstract:

OBJECTIVES: Rheumatoid arthritis (RA) shares some similar clinical and pathological features with juvenile idiopathic arthritis (JIA); indeed, the strategy of investigating whether RA susceptibility loci also confer susceptibility to JIA has already proved highly successful in identifying novel JIA loci. A plethora of newly validated RA loci has been reported in the past year. Therefore, the aim of this study was to investigate these single nucleotide polymorphisms (SNP) to determine if they...

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Journal:
Annals of the rheumatic diseases More from this journal
Volume:
71
Issue:
7
Pages:
1117-1121
Publication date:
2012-07-01
DOI:
EISSN:
1468-2060
ISSN:
0003-4967

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