Journal article
[Recombinant adenovirus-mediated gene transfer suppresses experimental arthritis]
- Abstract:
-
Collagen Induced Arthritis (CIA) is a widely studied animal model to develop and test novel therapeutic approaches for treating Rheumatoid Arthritis (RA) in humans. Soluble Cytotoxic T-Lymphocyte Antigen 4 (CTLA4-Ig), which binds B7 molecule on antigen presenting cells and blocks CD28 mediated T-lymphocyte activation, has been shown to ameliorate experimental autoimmune diseases such as lupus, diabetes and CIA. Objective of our research was to investigate in vivo the effectiveness of blocking...
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Bibliographic Details
- Journal:
- Reumatismo
- Volume:
- 53
- Issue:
- 1
- Pages:
- 46-54
- Publication date:
- 2001-01-01
- EISSN:
-
0048-7449
- ISSN:
-
0048-7449
- Source identifiers:
-
224033
Item Description
- Language:
- Italian
- Pubs id:
-
pubs:224033
- UUID:
-
uuid:ab9b9c16-2a24-486f-9a03-17999327e5e9
- Local pid:
- pubs:224033
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2001
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