- Abstract:
-
Collagen Induced Arthritis (CIA) is a widely studied animal model to develop and test novel therapeutic approaches for treating Rheumatoid Arthritis (RA) in humans. Soluble Cytotoxic T-Lymphocyte Antigen 4 (CTLA4-Ig), which binds B7 molecule on antigen presenting cells and blocks CD28 mediated T-lymphocyte activation, has been shown to ameliorate experimental autoimmune diseases such as lupus, diabetes and CIA. Objective of our research was to investigate in vivo the effectiveness of blocking...
Expand abstract - Journal:
- Reumatismo
- Volume:
- 53
- Issue:
- 1
- Pages:
- 46-54
- Publication date:
- 2001-01-01
- EISSN:
-
0048-7449
- ISSN:
-
0048-7449
- URN:
-
uuid:ab9b9c16-2a24-486f-9a03-17999327e5e9
- Source identifiers:
-
224033
- Local pid:
- pubs:224033
- Language:
- Italian
- Copyright date:
- 2001
Journal article
[Recombinant adenovirus-mediated gene transfer suppresses experimental arthritis]
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