Journal article
Cytomegalovirus (CMV) epitope-specific CD4(+) T cells are inflated in HIV(+) CMV(+) subjects
- Abstract:
-
Select CMV epitopes drive life-long CD8(+) T cell memory inflation, but the extent of CD4 memory inflation is poorly studied. CD4(+) T cells specific for human CMV (HCMV) are elevated in HIV(+) HCMV(+) subjects. To determine whether HCMV epitope-specific CD4(+) T cell memory inflation occurs during HIV infection, we used HLA-DR7 (DRB1*07:01) tetramers loaded with the glycoprotein B DYSNTHSTRYV (DYS) epitope to characterize circulating CD4(+) T cells in coinfected HLA-DR7(+) long-term nonprogr...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.4049/jimmunol.1700851
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Authors
Funding
+ National Institutes of Health
More from this funder
Grant:
P30AI110527
(toS.A.M.),P01AI030731
R01AI094019(toD.M.K.),P50GM115305
(toE.J.P.),T32AI007474(toS.A.K.),P01AI030731(toLawrenceCorey,principal
investigator),UL1TR000445(toGordonBernard,principalinvestigator),
HHSN272201300006C(totheNIHTetramerCoreFacility
+ National
Institute of General Medical Sciences
More from this funder
Grant:
T32 GM007347 (to C.O.A.
Bibliographic Details
- Publisher:
- American Association of Immunologists Publisher's website
- Journal:
- Journal of Immunology Journal website
- Volume:
- 199
- Issue:
- 9
- Pages:
- 3187-3201
- Publication date:
- 2017-10-23
- Acceptance date:
- 2017-08-28
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Pmid:
-
28972094
- Source identifiers:
-
732938
Item Description
- Language:
- English
- Pubs id:
-
pubs:732938
- UUID:
-
uuid:ab9a1b04-dfcf-43a7-8da9-ae3f23a98fba
- Local pid:
- pubs:732938
- Deposit date:
- 2017-10-20
Terms of use
- Copyright holder:
- American Association of Immunologists, Inc
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 by The American Association of Immunologists, Inc.
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