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Rabbit-specific computational modelling of ventricular cell electrophysiology: Using populations of models to explore variability in the response to ischemia.

Abstract:

Computational modelling, combined with experimental investigations, is a powerful method for investigating complex cardiac electrophysiological behaviour. The use of rabbit-specific models, due to the similarities of cardiac electrophysiology in this species with human, is especially prevalent. In this paper, we first briefly review rabbit-specific computational modelling of ventricular cell electrophysiology, multi-cellular simulations including cellular heterogeneity, and acute ischemia. Th...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.pbiomolbio.2016.06.003

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Institution:
University of Oxford
Department:
Oxford, MPLS, Computer Science
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Computer Science
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Computer Science
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Funding agency for:
Rodríguez, B
Publisher:
Elsevier Publisher's website
Journal:
Progress in biophysics and molecular biology Journal website
Publication date:
2016
DOI:
EISSN:
1873-1732
ISSN:
0079-6107
URN:
uuid:ab9966ba-a90b-4c03-978f-f8d15c958e4c
Source identifiers:
630910
Local pid:
pubs:630910

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