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Rabbit-specific computational modelling of ventricular cell electrophysiology: Using populations of models to explore variability in the response to ischemia.

Abstract:

Computational modelling, combined with experimental investigations, is a powerful method for investigating complex cardiac electrophysiological behaviour. The use of rabbit-specific models, due to the similarities of cardiac electrophysiology in this species with human, is especially prevalent. In this paper, we first briefly review rabbit-specific computational modelling of ventricular cell electrophysiology, multi-cellular simulations including cellular heterogeneity, and acute ischemia. Th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Role:
Author
More from this funder
Name:
Wellcome Trust
Funding agency for:
Rodríguez, B
Grant:
Senior Research fellowship in Basic Biomedical Sciences (100246/Z/12/Z
More from this funder
Name:
Engineering and Physical Sciences Research Council
Funding agency for:
Gemmell, P
Grant:
EP/G03706X/1
Publisher:
Elsevier
Journal:
Progress in biophysics and molecular biology More from this journal
Publication date:
2016-01-01
Acceptance date:
2016-06-13
DOI:
EISSN:
1873-1732
ISSN:
0079-6107
Language:
English
Keywords:
Pubs id:
pubs:630910
UUID:
uuid:ab9966ba-a90b-4c03-978f-f8d15c958e4c
Local pid:
pubs:630910
Source identifiers:
630910
Deposit date:
2016-07-06

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