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Functionalised pyrrolidinones derived from (S)-pyroglutamic acid by cycloaddition reactions

Abstract:
The α,β-unsaturatcd bicyclic lactams 3a,c, prepared from (S)-pyroglutamic acid, are useful substrates for cycloaddition reactions, giving excellent regio- and diastereocontrol; however, lactam 3c has very superior reactivity with several dienes and dipoles under mild reaction conditions.
Publication status:
Published

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Authors


Bailey, JH More by this author
Cherry, DT More by this author
Crapnell, KM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
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Journal:
TETRAHEDRON
Volume:
53
Issue:
34
Pages:
11731-11744
Publication date:
1997-08-25
DOI:
ISSN:
0040-4020
URN:
uuid:ab835758-06af-47be-beee-e46358288487
Source identifiers:
45688
Local pid:
pubs:45688
Language:
English

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