- Abstract:
-
Abstract Iron is an essential nutrient in several biological processes such as oxygen transport, DNA replication and erythropoiesis. Plasma iron normally circulates bound to transferrin. In iron overload disorders, however, iron concentrations exceed transferrin binding capacity and iron appears complexed with low molecular weight molecules, known as non-transferrin-bound iron (NTBI). NTBI is responsible for the toxicity associated with iron-overload pathologies but the mechanisms leading to ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1371/journal.pone.0079870
-
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- Role:
- Editor
- Department:
- Basic and Clinical Research on Iron Biology, IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal.
- Journal:
- PloS one
- Issue:
- 11
- Publication date:
- 2013-01-02
- Acceptance date:
- 2013-09-27
- DOI:
- ISSN:
-
1932-6203
- Pubs id:
-
pubs:562462
- URN:
-
uri:ab7eaf78-4bb3-41f4-b7bd-f6d67c3bc363
- UUID:
-
uuid:ab7eaf78-4bb3-41f4-b7bd-f6d67c3bc363
- Local pid:
- pubs:562462
- Language:
- English
- Keywords:
- Copyright holder:
- Arezes, J. [et. al.]
- Copyright date:
- 2013
- License:
- CC BY
Journal article
Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species.
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Authors
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+ Mattei, F
+
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