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Ultrasensitive impedimetric immunosensor for the detection of C-reactive protein in blood at surface-initiated-reversible addition–fragmentation chain transfer generated poly(2-hydroxyethyl methacrylate) brushes

Abstract:

The reversible addition–fragmentation chain transfer (RAFT) polymerization of 2-hydroxethyl methacrylate (HEMA) from a surface confined, dithio-tethered, chain transfer agent (CTA) enables the preparation of electrode-tethered poly(2-hydroxyethyl methacrylate) (pHEMA) brushes of well-defined thickness with convenience and exceptionally high interfacial impedimetric baseline stability. The subsequent covalent integration of antibodies generates interfaces of very high target recognition specif...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0003-2414-6197
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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author
ORCID:
0000-0001-7734-1709
Publisher:
American Chemical Society
Journal:
Analytical Chemistry More from this journal
Volume:
92
Issue:
7
Pages:
4707-4710
Publication date:
2020-03-19
Acceptance date:
2020-03-19
DOI:
EISSN:
1520-6882
ISSN:
0003-2700
Pmid:
32189499
Language:
English
Keywords:
Pubs id:
1096831
Local pid:
pubs:1096831
Deposit date:
2020-04-17

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