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The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study.

Abstract:

AIMS/HYPOTHESIS: Although a family history of type 2 diabetes is a strong risk factor for the disease, the factors mediating this excess risk are poorly understood. In the InterAct case-cohort study, we investigated the association between a family history of diabetes among different family members and the incidence of type 2 diabetes, as well as the extent to which genetic, anthropometric and lifestyle risk factors mediated this association. METHODS: A total of 13,869 individuals (including ...

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Publication status:
Published

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Publisher copy:
10.1007/s00125-012-2715-x

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Journal:
Diabetologia
Volume:
56
Issue:
1
Pages:
60-69
Publication date:
2013-01-01
DOI:
EISSN:
1432-0428
ISSN:
0012-186X
Source identifiers:
436414

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