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Journal article

RecA bundles mediate homology pairing between distant sisters during DNA break repair

Abstract:

DNA double-strand break (DSB) repair by homologous recombination has evolved to maintain genetic integrity in all organisms. Although many reactions that occur during homologous recombination are known, it is unclear where, when and how they occur in cells. Here, by using conventional and super-resolution microscopy, we describe the progression of DSB repair in live Escherichia coli. Specifically, we investigate whether homologous recombination can occur efficiently between distant sister loc...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/nature12868

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
ORCID:
0000-0002-1612-9699
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Publisher:
Nature Research
Journal:
Nature More from this journal
Volume:
506
Issue:
7487
Pages:
249-253
Publication date:
2013-12-22
Acceptance date:
2013-11-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Keywords:
Pubs id:
pubs:449687
UUID:
uuid:ab596a32-2925-4b4c-b674-24b28999bb5a
Local pid:
pubs:449687
Source identifiers:
449687
Deposit date:
2019-07-03

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