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Journal article

Genetic variation at the TNF locus and the risk of severe sequelae of ocular Chlamydia trachomatis infection in Gambians.

Abstract:

Tumor necrosis factor (TNF) is thought to be a key mediator of the inflammatory and fibrotic response to Chlamydia trachomatis (Ct) infection. A large matched-pair case-control study investigated putative functional single nucleotide polymorphisms (SNPs) across the major histocompatibility complex (MHC) class III region, including TNF and its immediate neighbors nuclear factor of kappa light polypeptide gene enhancer in B cells (IkappaBL), inhibitor like 1 and lymphotoxin alpha (LTA) in relat...

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Publication status:
Published

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Publisher copy:
10.1038/sj.gene.6364384

Authors


Natividad, A More by this author
Hanchard, N More by this author
Holland, MJ More by this author
Diakite, M More by this author
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Journal:
Genes and immunity
Volume:
8
Issue:
4
Pages:
288-295
Publication date:
2007-06-05
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
URN:
uuid:ab529dc0-019d-4e6a-905a-6584f8d9268b
Source identifiers:
40377
Local pid:
pubs:40377

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