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Gene set analysis exploiting the topology of a pathway.

Abstract:

BACKGROUND: Recently, a great effort in microarray data analysis is directed towards the study of the so-called gene sets. A gene set is defined by genes that are, somehow, functionally related. For example, genes appearing in a known biological pathway naturally define a gene set. The gene sets are usually identified from a priori biological knowledge. Nowadays, many bioinformatics resources store such kind of knowledge (see, for example, the Kyoto Encyclopedia of Genes and Genomes, among o...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1752-0509-4-121

Authors


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Institution:
University of Oxford
Department:
Oxford, MPLS, Statistics
Chiogna, M More by this author
Romualdi, C More by this author
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Funding agency for:
Massa, MS
Publisher:
BioMed Central Ltd. Publisher's website
Journal:
BMC systems biology Journal website
Volume:
4
Pages:
121
Publication date:
2010-09-01
DOI:
EISSN:
1752-0509
ISSN:
1752-0509
URN:
uuid:ab3af0f3-b2ba-43b5-8c7b-54f202d1d612
Source identifiers:
104715
Local pid:
pubs:104715

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