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Evidence for over-dispersion in the distribution of clinical malaria episodes in children

Abstract:

Background: It may be assumed that patterns of clinical malaria in children of similar age under the same level of exposure would follow a Poisson distribution with no over-dispersion. Longitudinal studies that have been conducted over many years suggest that some children may experience more episodes of clinical malaria than would be expected. The aim of this study was to identify this group of children and investigate possible causes for this increased susceptibility. Methodology and princi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
"Kenya Medical Research Institute, Centre for Geographic Medicine Research, Coast/Wellcome Trust Collaborative Program, Kilifi, Kenya"
Role:
Author
More by this author
Institution:
"Kenya Medical Research Institute, Centre for Geographic Medicine Research, Coast/Wellcome Trust Collaborative Program, Kilifi, Kenya", "London School of Hygiene and Tropical Medicine, London, UK"
Department:
Infectious Diseases Epidemiology Unit,Department of Population Health
Role:
Author
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Institution:
"Kenya Medical Research Institute, Centre for Geographic Medicine Research, Coast/Wellcome Trust Collaborative Program, Kilifi, Kenya", "University of Oxford"
Department:
Medical Sciences Division - Clinical Vaccinology and Tropical Medicine,Centre for (CCVTM)
Role:
Author
More by this author
Institution:
"Kenya Medical Research Institute, Centre for Geographic Medicine Research, Coast/Wellcome Trust Collaborative Program, Kilifi, Kenya", "University of Oxford"
Department:
Medical Sciences Division - Clinical Vaccinology and Tropical Medicine,Centre for (CCVTM)
Role:
Author
More by this author
Institution:
"University of Oxford", "Kenay Medical Research Institute/ WellcomeTrust Collaborative Program, Nairobi, Kenya"
Department:
Medical Sciences Division - Clinical Vaccinology and Tropical Medicine,Centre for (CCVTM)
Role:
Author

Contributors

Institution:
"Queensland Institute of Medical Research, Australia"
Role:
Editor
More from this funder
Name:
"Wellcome Trust", "European Network 6 BioMalpar Consortium"
Funding agency for:
Williams, T
Grant:
076934
More from this funder
Name:
Wellcome Trust
Funding agency for:
Marsh, K
Snow, R
Grant:
631342
079080
Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Volume:
3
Issue:
5
Article number:
e2196
Publication date:
2008-05-01
DOI:
EISSN:
1932-6203
Language:
English
Subjects:
UUID:
uuid:ab2e5116-a667-4c96-a34f-5a0403a40de9
Local pid:
ora:2770
Deposit date:
2009-04-30

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