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Journal article

Viral perturbations of host networks reflect disease etiology

Abstract:

Many human diseases, arising from mutations of disease susceptibility genes (genetic diseases), are also associated with viral infections (virally implicated diseases), either in a directly causal manner or by indirect associations. Here we examine whether viral perturbations of host interactome may underlie such virally implicated disease relationships. Using as models two different human viruses, Epstein-Barr virus (EBV) and human papillomavirus (HPV), we find that host targets of viral pro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
Public Library of Science
Journal:
PLoS Computational Biology More from this journal
Volume:
8
Issue:
6
Pages:
e1002531
Publication date:
2012-06-28
Acceptance date:
2012-03-28
DOI:
EISSN:
1553-7358
ISSN:
1553-734X
Language:
English
Keywords:
UUID:
uuid:ab2730c2-dd7b-4ac1-b437-7cedd3a8fcec
Local pid:
pubs:341228
Source identifiers:
341228
Deposit date:
2014-09-24

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