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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

Abstract:

Several risk factors for Crohn's disease have been identified in recent genome-wide association studies. To advance gene discovery further, we combined data from three studies on Crohn's disease (a total of 3,230 cases and 4,829 controls) and carried out replication in 3,664 independent cases with a mixture of population-based and family-based controls. The results strongly confirm 11 previously reported loci and provide genome-wide significant evidence for 21 additional loci, including the r...

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Publication status:
Published

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Publisher copy:
10.1038/ng.175

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Journal:
Nature genetics More from this journal
Volume:
40
Issue:
8
Pages:
955-962
Publication date:
2008-08-01
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
Language:
English
Keywords:
Pubs id:
pubs:97492
UUID:
uuid:ab25b55e-6edf-4037-b9d3-058c8e785d37
Local pid:
pubs:97492
Source identifiers:
97492
Deposit date:
2012-12-19

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