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Immunologic unresponsiveness to alloantigen in vivo: a role for regulatory T cells.

Abstract:

Exposure to alloantigen in vivo or in vitro induces alloantigen reactive regulatory T cells that can control transplant rejection. The mechanisms that underpin the activity of alloantigen reactive regulatory T cells in vivo are common with those of regulatory T cells that prevent autoimmunity. The identification and characterization of regulatory T cells that control rejection and contribute to the induction of immunologic unresponsiveness to alloantigens in vivo has opened up exciting opport...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Journal:
Immunological reviews More from this journal
Volume:
241
Issue:
1
Pages:
119-132
Publication date:
2011-05-01
DOI:
EISSN:
1600-065X
ISSN:
0105-2896
Language:
English
Keywords:
Pubs id:
pubs:136006
UUID:
uuid:ab2180c9-04b1-452d-8f41-0957be5598b3
Local pid:
pubs:136006
Source identifiers:
136006
Deposit date:
2012-12-19

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