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Do inflammatory biomarkers add to the discrimination of cardiovascular disease after allowing for social deprivation? Results from a 10-year cohort study in Glasgow, Scotland.

Abstract:

AIMS: To assess the additional discriminative value of adding each of five inflammatory biomarkers to the ASSIGN risk score, which includes social deprivation. METHODS AND RESULTS: In this study, 1319 men and women aged 25-64 in the fourth Glasgow MONICA study were followed-up for cardiovascular endpoints. Baseline C-reactive protein, fibrinogen, IL-6, IL-18, and TNFα were related to risk of CVD. The discriminative value of adding each to the ASSIGN score was assessed using area under the re...

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Publisher copy:
10.1093/eurheartj/ehp115

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Institution:
University of Oxford
Department:
Oxford
Role:
Author
Journal:
European heart journal More from this journal
Volume:
31
Issue:
21
Pages:
2669-2675
Publication date:
2010-11-01
DOI:
EISSN:
1522-9645
ISSN:
0195-668X
Language:
English
Keywords:
Pubs id:
pubs:435743
UUID:
uuid:ab1e986a-abcf-403c-836b-d93ff928fee2
Local pid:
pubs:435743
Source identifiers:
435743
Deposit date:
2013-11-16

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