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Reduction in infarct size, arrhythmias and chest pain by early intravenous beta blockade in suspected acute myocardial infarction.

Abstract:

Four hundred seventy-seven patients suspected of having had acute myocardial infarction within less than 12 hours were randomized to receive i.v. atenolol followed by oral treatment for 10 days or to a control group. In patients with ECG changes indicative of infarction at entry, i.v. atenolol significantly reduced enzyme release by one-third and enhanced R-wave preservation. In patients without such ECG changes, treatment significantly prevented the development of infarction in a proportion ...

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Authors


Sleight, P More by this author
Ramsdale, D More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
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Journal:
Circulation
Volume:
67
Issue:
6 Pt 2
Pages:
I32-I41
Publication date:
1983-06-05
EISSN:
1524-4539
ISSN:
0009-7322
URN:
uuid:ab1e19df-c323-463f-8ca3-ab37533e3f78
Source identifiers:
368154
Local pid:
pubs:368154

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