Journal article
Distribution and metabolism in healthy volunteers of disodium azodisalicylate, a potential therapeutic agent for ulcerative colitis.
- Abstract:
-
A series of experiments has been performed in healthy male volunteers to investigate the disposition of orally administered disodium azodisalicylate, a potentially useful drug for the treatment of ulcerative colitis. The drug was given by mouth in doses of up to 2 g a day for six weeks and there were no adverse effects. Serum concentrations of the intact compound were low and the serum half-time was 4-12.8 days, probably because of a combination of a low clearance rate and a high apparent vol...
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- Publication status:
- Published
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- Publisher copy:
- 10.1136/gut.23.12.1081
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Authors
Bibliographic Details
- Journal:
- Gut
- Volume:
- 23
- Issue:
- 12
- Pages:
- 1081-1087
- Publication date:
- 1982-12-05
- DOI:
- EISSN:
-
1468-3288
- ISSN:
-
0017-5749
- URN:
-
uuid:ab1a3dc2-1f9d-42eb-81f0-f408505ca648
- Source identifiers:
-
322104
- Local pid:
- pubs:322104
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 1982
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