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Journal article

Invasion pathways and malaria severity in Kenyan Plasmodium falciparum clinical isolates.

Abstract:

The invasion of erythrocytes by Plasmodium falciparum occurs through multiple pathways that can be studied in vitro by examining the invasion of erythrocytes treated with enzymes such as neuraminidase, trypsin, and chymotrypsin. We have studied the invasion pathways used by 31 Kenyan P. falciparum isolates from children with uncomplicated or severe malaria. Six distinct invasion profiles were detected, out of eight possible profiles. The majority of isolates (23 of 31) showed neuraminidase-re...

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Publication status:
Published

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Publisher copy:
10.1128/iai.00249-07

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Journal:
Infection and immunity More from this journal
Volume:
75
Issue:
6
Pages:
3014-3020
Publication date:
2007-06-01
DOI:
EISSN:
1098-5522
ISSN:
0019-9567
Language:
English
Keywords:
Pubs id:
pubs:140101
UUID:
uuid:ab0810e0-3950-478b-a736-b93410ff6a0a
Local pid:
pubs:140101
Source identifiers:
140101
Deposit date:
2012-12-19

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