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A mechanochemical model for adult dermal wound contraction and the permanence of the contracted tissue displacement profile.

Abstract:

The healing of adult mammalian skin wounds involves a complex sequence of spatially and temporally coordinated processes. Wound contraction, by reducing the size of the injury, is an intrinsic component of full-thickness excisional dermal wound healing. The underlying biomechanics of wound contraction, however, are not fully understood, and little is known about the pathogenesis of severe medical conditions known as fibrocontractive diseases. The aim of this work is to investigate a determini...

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Publication status:
Published

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Publisher copy:
10.1006/jtbi.1995.0230

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Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Role:
Author
Journal:
Journal of theoretical biology
Volume:
177
Issue:
2
Pages:
113-128
Publication date:
1995-11-05
DOI:
EISSN:
1095-8541
ISSN:
0022-5193
URN:
uuid:aaf1eba5-fa6c-4a4c-a774-1cb1ab81fe2e
Source identifiers:
8957
Local pid:
pubs:8957

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