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Discovery and analysis of the first endogenous lentivirus.

Abstract:

The lentiviruses are associated with a wide range of chronic diseases in mammals. These include immunodeficiencies (such as HIV/AIDS in humans), malignancies, and lymphatic and neurological disorders in primates, felids, and a variety of wild and domesticated ungulates. Evolutionary analyses of the genomic sequences of modern-day lentiviruses have suggested a relatively recent date for their emergence, but the failure to identify any endogenous, vertically transmitted examples has meant that ...

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Publisher copy:
10.1073/pnas.0700471104

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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
104
Issue:
15
Pages:
6261-6265
Publication date:
2007-04-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:aaf1213b-8b81-4016-a9fa-0b12a623e7b4
Source identifiers:
209277
Local pid:
pubs:209277

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