Journal article
Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes.
- Abstract:
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Metabolic Syndrome (MetS) is highly prevalent and has considerable public health impact, but its underlying genetic factors remain elusive. To identify gene networks involved in MetS, we conducted whole-genome expression and genotype profiling on abdominal (ABD) and gluteal (GLU) adipose tissue, and whole blood (WB), from 29 MetS cases and 44 controls. Co-expression network analysis for each tissue independently identified nine, six, and zero MetS-associated modules of coexpressed genes in AB...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.2MB)
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- Publisher copy:
- 10.1371/journal.pgen.1002505
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Authors
Funding
European Community
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS genetics Journal website
- Volume:
- 8
- Issue:
- 2
- Article number:
- e1002505
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
-
1553-7404
- ISSN:
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1553-7390
- Source identifiers:
-
313015
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:aae03bfd-de09-4542-a2f7-8a340d027533
- Local pid:
- pubs:313015
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Min et al
- Copyright date:
- 2012
- Notes:
- Copyright 2012 Min et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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