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Novel Plasmodium falciparum clones and rising clone multiplicities are associated with the increase in malaria morbidity in Ghanaian children during the transition into the high transmission season.

Abstract:

A survey of Plasmodium falciparum infection and clone multiplicity in Ghanaian children was carried out to study the effect of the onset of the malaria transmission season on disease incidence. Fortnightly blood samples were collected from 40 children living in the rural town of Dodowa, between February and August 1998. P. falciparum parasite densities were calculated and PCR genotyping was carried out using the polymorphic MSP-1 and MSP-2 genes as target loci for the estimation of the number...

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Publication status:
Published

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Publisher copy:
10.1017/s0031182001008162

Authors


Ofosu-Okyere, A More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Nkrumah, F More by this author
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Journal:
Parasitology
Volume:
123
Issue:
Pt 2
Pages:
113-123
Publication date:
2001-08-05
DOI:
EISSN:
1469-8161
ISSN:
0031-1820
URN:
uuid:aad8ec95-3d91-48ef-b1c0-ef4d4e2d19c1
Source identifiers:
90463
Local pid:
pubs:90463

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