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Two-photon photodynamic therapy and its potential application to age related macular degeneration

Abstract:

Photodynamic therapy (PDT) using verteporfin is widely used for treatment of age related macular degeneration (AMD). Due to non-perfect selectivity of the drug accumulation in the neovasculature some collateral damage to healthy tissue arises during the treatment. Damage to healthy structures in the eye is always a concern because of a high probability of reducing visual acuity. Two-photon (2-γ) photodynamic therapy potentially offers much higher treatment selectivity than its one-photon (1-γ...

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Publisher copy:
10.1117/12.701086

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Journal:
Progress in Biomedical Optics and Imaging - Proceedings of SPIE More from this journal
Volume:
6427
Publication date:
2007-01-01
DOI:
ISSN:
1605-7422
Language:
English
Keywords:
Pubs id:
pubs:331923
UUID:
uuid:aabf19db-380c-42be-8cad-fd5100aa6b26
Local pid:
pubs:331923
Source identifiers:
331923
Deposit date:
2012-12-19

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