- Abstract:
-
We have reported previously that the herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) fused with green fluorescent protein (GFP) is localized in the nucleus of HSV-1 TK-GFP gene-transfected cells (Degrève et al. (1998) J. Virol. 72, 9535-9543). Deletion of the N-terminal 34 amino acids or selective mutation of the nonapeptide (25)RRTALRPRR(33), located in the N-terminal region of HSV-1 TK, resulted in the loss of the specific nuclear localization of HSV-1 TK. Utilizing information on...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1006/bbrc.1999.1485
-
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- Journal:
- Biochemical and biophysical research communications
- Volume:
- 264
- Issue:
- 2
- Pages:
- 338-342
- Publication date:
- 1999-10-05
- DOI:
- EISSN:
-
1090-2104
- ISSN:
-
0006-291X
- URN:
-
uuid:aaae5b91-86ed-417f-8a2a-92ae0e918889
- Source identifiers:
-
28223
- Local pid:
- pubs:28223
- Language:
- English
- Keywords:
- Copyright date:
- 1999
Journal article
Characterization of multiple nuclear localization signals in herpes simplex virus type 1 thymidine kinase.
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