- Abstract:
-
Despite evidence for an abnormality of noradrenergic function in schizophrenia, it remains unclear whether the number of noradrenergic neurones is normal in patients with the disorder. In postmortem, formalin-fixed tissue from 15 schizophrenic patients and 18 controls matched for age and gender, we made estimates of the number and size of tyrosine-hydroxylase-immunoreactive cells in the locus coeruleus (LC). No significant difference was detected between these groups in the cross-sectional ar...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1365-2990.2004.00597.x
-
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- Journal:
- Neuropathology and applied neurobiology
- Volume:
- 31
- Issue:
- 2
- Pages:
- 115-126
- Publication date:
- 2005-04-05
- DOI:
- EISSN:
-
1365-2990
- ISSN:
-
0305-1846
- URN:
-
uuid:aa99ed2a-adbd-469b-91ed-238c1c047eb1
- Source identifiers:
-
242717
- Local pid:
- pubs:242717
- Language:
- English
- Keywords:
- Copyright date:
- 2005
Journal article
The locus coeruleus in schizophrenia: a postmortem study of noradrenergic neurones.
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