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Use of oral bisphosphonates and risk of hospital admission with osteonecrosis of the jaw: Large prospective cohort study in UK women

Abstract:

About 1 in 10 postmenopausal UK women are currently prescribed oral bisphosphonates, but there are concerns about their adverse effects. Osteonecrosis of the jaw is a recognised uncommon but important side effect of intravenous bisphosphonates, but epidemiological evidence on risk of osteonecrosis of the jaw associated with oral bisphosphonate use is less conclusive. The incidence of hospital admission with osteonecrosis of the jaw was examined among 521,695 Million Women Study participants,...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.bone.2019.04.003

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Population Health
Role:
Author
ORCID:
0000-0002-5753-907X
More by this author
Institution:
University of Oxford
Department:
Nuffield Dept of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Nuffield Dept of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Nuffield Dept of Population Health
Sub department:
Cancer Epidemiology Unit
Role:
Author
Publisher:
Elsevier
Journal:
Bone More from this journal
Volume:
124
Pages:
69-74
Publication date:
2019-04-05
Acceptance date:
2019-04-04
DOI:
EISSN:
1873-2763
ISSN:
8756-3282
Pmid:
30959190
Language:
English
Keywords:
Pubs id:
pubs:992118
UUID:
uuid:aa5b1bba-078d-4512-a334-3a7de92d39b2
Local pid:
pubs:992118
Source identifiers:
992118
Deposit date:
2019-04-23

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