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Cyclin E and p27: Their putative role as prognostic markers

Abstract:

Abnormalities or derangements of the orderly proliferation and cycling of cells is the quintessential definition of a cancer or malignant cell. The complex nature of the interaction of several interdependent cell cycle proteins has and continues to be unravelled. Key functions have been ascribed to many of the proteins and the delicate balance that maintains cell normal cell cycling is now understood. Within the cell cycle, the GI proteins have come under intense scrutiny, especially the inte...

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences, Biomedical Research Centre
Journal:
Current Diagnostic Pathology
Volume:
8
Issue:
5
Pages:
289-296
Publication date:
2002-10-05
DOI:
ISSN:
0968-6053
URN:
uuid:aa58732a-e6c3-4219-bdea-614030f06c14
Source identifiers:
122244
Local pid:
pubs:122244

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