Journal article
Targeting MAPK (Ras/ERK) and PI3K/Akt pathways in pituitary tumorigenesis.
- Abstract:
-
BACKGROUND: Pituitary adenomas are common intracranial neoplasms, comprising 10 - 15% of all brain tumors. Data from autopsy studies suggest that pituitary adenomas develop in 17 - 25% of the population. Nevertheless, the pathogenesis of sporadic pituitary tumors still remains obscure. OBJECTIVE: In this review, the roles of MAPK (mainly Ras/extracellular signal-regulated protein kinase (ERK)) and PI3K/Akt signaling pathways in pituitary tumorigenesis are summarised. METHODS: A full data sea...
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- Publication status:
- Published
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- Publisher copy:
- 10.1517/14728220903170675
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Bibliographic Details
- Journal:
- Expert opinion on therapeutic targets
- Volume:
- 13
- Issue:
- 9
- Pages:
- 1121-1134
- Publication date:
- 2009-09-01
- DOI:
- EISSN:
-
1744-7631
- ISSN:
-
1472-8222
- Source identifiers:
-
138617
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:138617
- UUID:
-
uuid:aa39bc00-6dd0-4019-8a84-4044332f19f4
- Local pid:
- pubs:138617
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
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